The Varshney Lab’s vision is to create a comprehensive ‘phenome’ resource by phenotyping mutations in every zebrafish gene, accelerating the discovery of gene functions and their implications for human health. We strive to contribute significantly to understanding and treating genetic diseases by integrating cutting-edge technologies and collaborative research.
Varshney lab’s research is centered on three main themes:
- Cutting-edge CRISPR-based Genome Editing Technologies: We are committed to developing and optimizing advanced genome editing tools, such as next-generation base editors, to facilitate precise genetic modifications and functional analysis of human disease-causing variants.
- Understanding Neurological Disorders and Hearing Impairment: We explore the genetic and molecular mechanisms underlying various neurological disorders and hearing impairments, aiming to translate our findings into therapeutic interventions.
- In Vivo Functional Analysis of Non-coding Variants from GWAS: Our lab is pioneering methods to investigate the functional impact of non-coding genetic variants identified through genome-wide association studies, shedding light on their roles in complex human diseases.
If you are interested in joining our group, please contact:
Gaurav K Varshney, Ph.D.
Associate Professor,
Genes & Human Disease Research Program
Oklahoma Medical Research Foundation
825 N.E. 13th Street
Office: S-310 Chapman Building
Lab: S-302,304,306,308
Oklahoma City, OK 73104
